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Update on Osteoporosis in Men

Posted on: 11/30/1999
In this review article, the prevalence and causes of osteoporosis in men are presented. Osteoporosis refers to decreased bone mass that can lead to brittle bones.

Many cases of osteoporosis are age-related. But sometimes there is no known cause. And osteoporosis in men can occur as a result of another condition such as alcoholism, hormone disorders, or use of certain medications.

In half of all cases of osteoporosis among men, there is a known cause. Several common problems linked with osteoporosis include rheumatoid arthritis and multiple myeloma or other forms of cancer.

The number of men affected by this disease is on the rise. It's estimated that hip fractures in men from osteoporosis will equal women by the year 2025. Because of this fact, the International Osteoporosis Foundation has launched a new campaign. It's called Invest in Your Bones.

In the future, men will be advised to have a bone density scan to establish a baseline and watch for changes. Men over the age of 70 should have this test. This is especially true if they have a family history of osteoporosis or if they smoke (or use other tobacco products). Symptoms such as loss of height, rounded spine, or back pain should be reported to the doctor.

Men who have prostate cancer or the prostate removed for any reason should be treated for bone loss. Calcium, vitamin D, and bisphosphonates are the main tools used to prevent loss of bone density. Bisphosphonates is a class of drugs that stops bone cells called osteoclasts. Osteoclasts resorb bone leading to weak and fragile bones.

More studies are needed regarding men and osteoporosis. Which drugs work best? When should treatment be started? Does it matter what the underlying cause of the osteoporosis is when prescribing medications? What are the long-term effects of hormone therapy?

These and other questions must be investigated and answered. This information is needed before specific management programs can be recommended with confidence for men with osteoporosis.

References:
Luigi Gennari, MD, PhD, and John P. Bilezikian, MD. Osteoporosis in Men: A Growing Cause for Concern. In The Journal of Musculoskeletal Medicine. November 2007. Vol. 24. No. 11. Pp. 461-470.

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