Osteoporosis is a common side effect of long-term androgen deprivation therapy (ADT). ADT also known as androgen ablation (AA) is used for prostate cancer. This treatment is based on the fact that the male hormone (androgen) causes tumor growth. The goal of AA is to block androgens such as testosterone and prevent tumor cells from growing. Long-term use of AA seems to work better than short courses of treatment.

On the down side, a lack of testosterone over time can result in osteoporosis. All men starting AA should get calcium and vitamin D. They are advised to keep up a moderate exercise program. A baseline bone density study should be done to keep track of bone mass. If osteoporosis develops, drugs to prevent bone loss can be used.

Talk to your doctor about ways to minimize the effects of osteoporosis. Diet, exercise, and drugs can help prevent bone loss from getting worse or resulting in bone fractures.