To take the medication safely and effectively, the pill should be taken on an empty stomach, first thing in the morning, with a full glass of water. At this point, it's very important to stay upright, either sitting or standing and not to lie down at all. In fact, it's so important that people who cannot sit upright or stand for 30 minutes shouldn't take these medications.

After 30 minutes, you can eat or drink, but it's still advised that if you are going to lie down, to make sure that you eat first. Following these instructions should reduce the chances of developing side effects like painful swallowing or heartburn.